Platelet Function Test–Guided Strategy

Platelet function test-guided strategy: lost in translation?

Cinnamon inhibits platelet function and improves cardiovascular system

Background: Cinnamon belongs to the Lauraceae family and is one of the most common spices that are used as traditional medicine in the world. The bark and leaf of cinnamon contain essential oils and derivatives including cinnamaldehyde, cinnamic acid and several other compounds such as polyphenols. Moreover, anti-inflammatory and lipid lowering properties of cinnamon has been proven. Objective:...

Platelet function analysis.

Since the last guidelines for BCSH platelet function testing were written in the late 1980s, many new tests have become available. Previously most platelet function tests were traditionally utilized to aid in the diagnosis and management of patients with platelet and haemostatic disorders. Most traditional tests were also largely restricted to the specialized laboratory or centre. However, nowa...

Platelet function in anaphylaxis.

Human platelets, following immunological or nonimmunological activation, are capable of releasing a variety of biologically active mediators and are able to actively participate in hypersensitivity reactions, including anaphylaxis. These cells constitutively express functional receptors for the Fc fragment of IgE, both the low affinity receptor (Fc epsilonRII) and the high affinity receptor (Fc...

Platelet function disorders.

Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery. As the complex internal biochemical and signal transduction pathways are further...